IMMUNE DYSFUNCTION (EID)
Eosinophilic immune dysfunction (EID) can be characterized as the dysregulation of biological mechanisms involved with eosinophil recruitment and activation.1
EOSINOPHILS ARE KEY EFFECTOR CELLS2
Activated eosinophils can contribute to disease pathology through several mechanisms and play a key role in the self-perpetuating cycle of inflammatory damage in a range of diseases.1-4
CYCLE OF EOSINOPHILIC INFLAMMATION1,5-7
ECP=eosinophil cationic protein; EDN=eosinophil-derived neurotoxin; EPX=eosinophil peroxidase; IL=interleukin; MBP=major base protein; TGF=transforming growth factor; T2=Type 2.